Institute for Clinical and Economic Review Report on Voretigene Neparvovec Suggests Substantial Price Discount Needed to Meet Traditional Cost-Effectiveness Standards

Press Release

–Special considerations include patient age, benefit durability, and rarity of condition–  –Report will be subject to public deliberation at January 25th Midwest CEPAC meeting– BOSTON, January 12, 2018 – The Institute for Clinical and Economic Review (ICER) today released its revised Evidence Report assessing the comparative clinical effectiveness and value of voretigene neparvovec (LuxturnaTM, Spark Therapeutics) for treatment of vision […]

Does Cost-Effectiveness Analysis Overvalue Potential Cures? Exploring Alternative Methods for Applying a “Shared Savings” Approach to Cost Offsets

Journal Article

Objectives: To evaluate alternative methods to calculate and/or attribute economic surplus in the cost-effectiveness analysis ofsingle or short-term therapies.Methods: We performed a systematic literature review of articles describing alternative methods for cost-effectivenessanalysis of potentially curative therapies whose assessment using traditional methods may suggest unaffordablevaluations owing to the magnitude of estimated long-term quality-adjusted life-year (QALY) gains […]

Cost-Effectiveness, the QALY, and the evLYG

Cost-Effectiveness, the QALY, and the evLYG Clinicians play a vital role in helping individual patients decide what treatment is best for them. In contrast, cost-effectiveness analysis looks at evidence for entire patient populations, comparing the health benefits and economic costs of different treatment options. The goal of cost-effectiveness analysis is to help inform policy so that treatments that […]

ICER to Assess Cost-Effectiveness of Trained Service Dogs for American Veterans with PTSD

Press Release

— Analysis has been commissioned by the U.S. Department of Veterans Affairs to help evaluate data from a completed clinical trial comparing patient outcomes with specially trained service dogs to outcomes with emotional support dogs without specialized training — — The final ICER report will be submitted to the National Academy of Medicine for deliberation […]

Institute for Clinical and Economic Review Finds Treatments Prevent Hereditary Angioedema Attacks, but Cost-Effectiveness Uncertain and Sensitive to Frequency of Attacks

Press Release

— As with all treatments for ultra-rare conditions, judgments of overall value require consideration of the broader patient benefits and contextual issues that will be discussed at the October 25 public meeting — BOSTON, October 11, 2018 – The Institute for Clinical and Economic Review (ICER) today released an Evidence Report assessing the comparative clinical effectiveness and value […]