Obesity Management

CTAF, Washington State

It is estimated that more than one-third of American adults and about 17% of adolescents are obese. The health effects of obesity are myriad and include the development of type 2 diabetes, hypertension, cardiovascular disease, cancer, high blood pressure, and sleep apnea. Obesity and its sequelae are estimated to generate $147 billion in health care costs in the US alone.  The complexity involved in managing obesity may affect both patient candidacy for certain treatment options as well as adherence to lifestyle changes necessary to sustain weight loss and improve health outcomes. Clinical interest is therefore high in treatments that may be used for patients at multiple levels of obesity, as well as in interventions that promote better adherence to lifestyle change.

Interventions of interest:

Devices
Temporary intragastric balloon systems (e.g., Silimed®, ReShape®)
• Vagus nerve block devices (e.g., Maestro® system)
• Duodenal-jejunal bypass liner (EndoBarrier®)
Medications
• Naltrexone/bupropion sustained-release (Contrave®)
• Phentermine/topiramate extended-release (Qsymia®)
• Lorcaserin (Belviq®)
• Liraglutide (Saxenda®)

Date of review: May 2015


Intervention of interest:

Roux-en-Y gastric bypass (RYGB)
Biliopancreatic diversion/duodenal switch (BPD/DS)
Laparoscopic adjustable gastric banding (LAGB)
Vertical sleeve gastrectomy (VSG)

Date of review: April 2015

ASSOCIATED MEETING & MATERIALS

CTAF
July 14, 2015 9:30am - 3:30pm PT

Location: The California Endowment, 1000 N. Alameda St., Los Angeles, CA 90012

The California Technology Assessment Forum (CTAF) held a public meeting on Tuesday, July 14, 2015 to discuss the comparative effectiveness and value of several current approaches to manage obesity, including medications, devices, and surgical procedures. ICER produced a report that includes a systematic review of the published evidence, as well as an economic analysis that examines cost-effectiveness and budget impact of the various approaches. The report formed the basis for deliberation and discussion at the public meeting, where the CTAF panel voted on key questions raised in the report, and a policy roundtable discussed evidence-based practice and policy recommendations.

Key Dates

Associated Materials

03/24/2015

05/25/2015 – 06/09/2015

Public comments received on the Draft Evidence Report.


05/26/2015

05/26/2015

05/26/2015

06/23/2015

06/23/2015

06/23/2015

06/23/2015

07/14/2015

08/14/2015

08/14/2015

08/14/2015
Webcast Recording Evidence Presentation and Public Comments

08/14/2015
Webcast Recording Deliberation and Voting

08/14/2015
Webcast Recording Policy Roundtable

08/14/2015

08/14/2015
Other Appendices

01/17/2017


Key Dates

Associated Materials